Home » Xenobiotic Metabolism And Disposition: The Design Of Studies On Novel Compounds by Harry P.A. Illing
Xenobiotic Metabolism And Disposition: The Design Of Studies On Novel Compounds Harry P.A. Illing

Xenobiotic Metabolism And Disposition: The Design Of Studies On Novel Compounds

Harry P.A. Illing

Published February 28th 1989
ISBN : 9780849361630
Hardcover
232 pages
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 About the Book 

This publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novelMoreThis publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic procedures are discussed, together with techniques for separating and identifying metabolites and metabolic path-ways. Information on when the procedures are appropriate, and examples of what they represent, are presented in order to illustrate the value of such stud-ies.